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A vicious cycle drives mitochondrial decay in aging

Beyond the Mitochondrial Tune Up: Part III

Part III: Restoring Mitophagy – the Key To Mitochondrial Rejuvenation Introduction Mitochondrial decay resulting from oxidative damage accumulates with age and is universally recognized as a major contributing factor to the whole range of functional decline and tissue deterioration associated with aging.1 2 3 4 5 6 7 Part I of this review discussed Bruce […]

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Mitochondrial Oxidative Phosphorylation (Electron Transport Chain)

Beyond the Mitochondrial Tune Up: Part II

Part II: The Methylation – Transsulfuration Connection to Mitochond Introduction Mitochondrial decay resulting from oxidative damage accumulates with age and is universally recognized as a major contributing factor to the whole range of functional decline and tissue deterioration associated with aging.1 2 3 4 5 6 7 Part I of this review discussed Bruce Ames’ […]

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Krebs Cycle

Beyond the Mitochondrial Tune Up: Part I

Part I: Delaying the Mitochondrial Decay of Aging Introduction Mitochondrial decay resulting from oxidative damage is known to accumulate with age and is universally recognized as a major contributing factor to the whole range of functional decline and tissue deterioration associated with aging.1 2 3 4 5 6 7 Age-associated changes in mitochondria are characterized […]

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Cardioprotective Strategies to Close the Statin Gap: “News to Use” from the Latest Research

Cardiovascular disease, which now afflicts more than 80 million Americans – 36.3% of the U.S. population, including 38,100,000 individuals ≥ 60 – continues to be the No. 1 cause of death in the U.S., despite widespread use of statins, which, in 2002,  were being taken by >30% of Medicare patients ≥ 65.1 Statins, the most […]

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Common Genetic Variants and Other Host-related Factors Greatly Increase Susceptibility to Vitamin A Deficiency

Women are at risk of vitamin A deficiency. In his presentation at the 2nd Hohenheim Nutrition Conference in Stuttgart, Germany, November 2009, Dr. Georg Lietz of England’s Newcastle University, the senior investigator in research published April 2009 in the FASEB Journal (and summarized in our June 2009 LMR review, “Vitamin A – Tolerance Extends Longevity”), […]

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