Part III: Restoring Mitophagy – the Key To Mitochondrial Rejuvenation Introduction Mitochondrial decay resulting from oxidative damage accumulates with age and is universally recognized as a major contributing factor to the whole range of functional decline and tissue deterioration associated with aging.1 2 3 4 5 6 7 Part I of this review discussed Bruce […]
Part II: The Methylation – Transsulfuration Connection to Mitochond Introduction Mitochondrial decay resulting from oxidative damage accumulates with age and is universally recognized as a major contributing factor to the whole range of functional decline and tissue deterioration associated with aging.1 2 3 4 5 6 7 Part I of this review discussed Bruce Ames’ […]
Abstract Cellular senescence, although protective when triggered in cells that have become cancerous, plays a key pathological role in other age-associated diseases and in so-called “healthy aging.” The age-associated increase in cellular senescence has been assumed to result from the cumulative effects of “wear and tear,” but genetic research has revealed that cellular senescence occurs […]
