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Chromosomes

Slowing Telomere Attrition and Cellular Senescence—Today: Part I

Abstract Cellular senescence, although protective when triggered in cells that have become cancerous, plays a key pathological role in other age-associated diseases and in so-called “healthy aging.” The age-associated increase in cellular senescence has been assumed to result from the cumulative effects of “wear and tear,” but genetic research has revealed that cellular senescence occurs […]

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